Synthesis and <i>in vivo</i> Evaluation of Fluorobenzyl Metformin Derivatives as Potential Drugs in the Diabetes Treatment

Diabetes, one of the most prevalent diseases among Mexican population, is our more important topics research to generate alternatives for its treatment. With ancient city Teotihuacan in background, we show generation novel, and previously non-described fluorobenzyl metformin derivates, represented as creation Quetzalcoatl a Xoloitzcuintle (brown dog), which are representatives culture. These compounds kept efficiency commercial metformin, nevertheless hepatotoxicity fatty acids levels significantly non-increased on mice vivo assays. More information can be found Research Article by Solorio-Alvarado, Rafael Ortíz-Alvarado et al.